Nominees

 Video of the Year

    * Amy Winehouse - "Rehab"
    * Beyoncé - "Irreplaceable"
    * Justice - "D.A.N.C.E."
    * Justin Timberlake - "What Goes Around...Comes Around"
    * Kanye West - "Stronger"
    * Rihanna - "Umbrella" featuring Jay-Z

 Male Artist of the Year

    * Akon - Don't Matter, I Wanna Love You featuring Snoop Dogg, Smack That featuring Eminem
    * Kanye West - "Can't Tell Me Nothing", "Stronger", "Classic (Better Than I've Ever Been" — DJ Premier remix, featuring Nas, KRS-One and Rakim)
    * Justin Timberlake - "Let Me Talk To You/ My Love" featuring T.I. and Timbaland, "SexyBack" featuring Timbaland, "What Goes Around...Comes Around"
    * T.I. - "Big Things Poppin' (Do It)", "You Know What It Is" featuring Wyclef Jean, "What You Know"
    * Robin Thicke - "Can U Believe", "Lost Without U", "Wanna Love You Girl" (remix) featuring Busta Rhymes and Pharrell

 Female Artist of the Year

    * Amy Winehouse - "Rehab", "You Know I'm No Good"
    * Beyoncé - "Irreplaceable", "Beautiful Liar" featuring Shakira
    * Fergie - "Big Girls Don't Cry (Personal)", "Glamorous" featuring Ludacris, "Fergalicious" featuring Will.I.Am
    * Nelly Furtado - Maneater", "Say It Right"
    * Rihanna: "Umbrella" featuring Jay-Z

 Best New Artist

    * Amy Winehouse - "Rehab" "You Know I'm No Good"
    * Carrie Underwood - "Before He Cheats"
    * Gym Class Heroes - "Clothes Off" featuring Patrick Stump, "Cupid's Chokehold/Breakfast in America" featuring Patrick Stump
    * Lily Allen: "Alfie", "Smile", "LDN"
    * Peter Bjorn and John: "Young Folks"

 Best Group

    * Fall Out Boy - "This Ain't A Scene, It's An Arms Race", "Thnks Fr Th Mmrs"
    * Gym Class Heroes - "Clothes Off" featuring Patrick Stump, "Cupid's Chokehold/Breakfast in America" featuring Patrick Stump
    * Linkin Park - "What I've Done"
    * Maroon 5 - "Makes Me Wonder"
    * White Stripes - "Icky Thump"

 Most Earthshattering Collaboration

    * Akon featuring Eminem - "Smack That"
    * Beyoncé feturing Shakira - "Beautiful Liar"
    * Justin Timberlake featuring Timbaland - "SexyBack"
    * Gwen Stefani featuring Akon - "The Sweet Escape"
    * U2 featuring Green Day - "The Saints Are Coming"

 Quadruple Threat of the Year

    * Beyoncé
    * Bono
    * Jay-Z
    * Justin Timberlake
    * Kanye West

 Monster Single of the Year

    * Avril Lavigne - "Girlfriend"
    * Daughtry - "Home"
    * Fall Out Boy - "Thnks Fr Th Mmrs"
    * Lil' Mama - "Lip Gloss (No Music)"
    * T-Pain featuring Yung Joc - "Buy U a Drank (Shawty Snappin')"
    * Timbaland featuring Keri Hilson, D.O.E. and Sebastian - "The Way I Are"
    * MIMS - "This Is Why I'm Hot"
    * Plain White T's - "Hey There Delilah"
    * Rihanna featuring Jay-Z - "Umbrella"
    * Shop Boyz - "Party Like a Rockstar"

 Best Director

    * Beyoncé featuring Shakira - "Beautiful Liar" - Director: Jake Nava
    * Christina Aguilera - "Candyman" - Directors: Matthew Rolston and Christina Aguilera
    * Justin Timberlake - "What Goes Around...Comes Around" - Director: Samuel Bayer
    * Kanye West - "Stronger" - Director: Hype Williams
    * Linkin Park - "What I've Done" Director: Joseph Hahn
    * Rihanna featuring Jay-Z - "Umbrella" - Director: Chris Applebaum

 Best Editing in a Video

    * Beyoncé and Shakira - "Beautiful Liar" - Editor: Jarett Figl
    * Gnarls Barkley - "Smiley Faces" - Editor: Ken Mowe
    * Justin Timberlake - "What Goes Around...Comes Around" - Editor: Hollee Singer
    * Kanye West - "Stronger" - Editors: Peter Johnson and Corey Weisz
    * Linkin Park - "What I've Done" - Editor: Igor Kovalik

 Best Choreography in a Video

    * Beyoncé and Shakira: "Beautiful Liar" - Choreographer: Frank Gatson
    * Chris Brown - "Wall To Wall" - Choreographers: Rich & Tone and Flii Styles
    * Ciara: "Like A Boy" - Choreographer Jamaica Craft
    * Eve - "Tambourine" - Choreographer: Tahesha Scott
    * Justin Timberlake featuring Timbaland - "SexyBack" - Choreographer: Marty Kuldeka

 Performers

    * Lily Allen
    * Chris Brown
    * Fall Out Boy
    * Foo Fighters
    * Rihanna
    * Timbaland
    * Justin Timberlake
    * Kanye West (confirmed to open the show on radio interview and his website)
    * Amy Winehouse